qiang chen-凯发k8官方网娱乐官方


  • title: ph. d., professor
  • department: institute of biochemistry and molecular biology
  • address: yifu biology building 1118
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  • email: [email protected]
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2004-     professor, school of life sciences, lanzhou university
1997-2004  associate professor, school of life sciences, lanzhou university
1990-1997  lecturer, department of biology, lanzhou university 
1983-1990  teaching assistant, department of biology, lanzhou university
1997-2001 school of life sciences, lanzhou university, ph. d.    
1995-1996 national institute of wildlife (istituto nazionale per la funa selvatica),italy, visiting scholar 
1987-1990 department of biology, lanzhou university, m.s. 
1979-1983 department of biology, lanzhou university, b.s.


academic appointments

中国生理学会比较生理学专业委员会副主任委员 2015-




administrative appointments



honors & awards



甘肃省高等学校实验室建设与管理先进工作者 2006

甘肃省教学成果二等奖  生物学实验技术队伍建设与本科生创新能力培养模式及实践 (排名第二) 2010

甘肃省教学成果二等奖  生物学野外实习改革与实践 (排名第二)2008

甘肃省自然科学二等奖 我国石鸡属鸟类分类、生态和生态遗传研究(排名第三) 2007


    1. 密点麻蜥性别决定机制的研究  国家自然科学基金面上项目,2007.1-2009.12,(主持)
    2. 三种沙蜥的性别决定机制以及孵化温度对其幼体生存能力影响的研究  国家自然科学基金面上项目,2011.1-2011.12(主持)
    3. 若干多肽合成和化学修饰的新方法和关键技术及其在多肽药物产业开发中的应用  国家科技重大专项 2009.1-2010.12(参加)
    4. 青海沙蜥和红尾沙蜥对高原低氧的适应机制研究 国家自然科学基金面上项目,2013-2016(主持)
    5. 红尾沙蜥适应和耐受低温的机制  国家自然科学基金面上项目,2015-2018(主持)




59. zhang, yang, shiwei liang, jianzheng he, yucheng bai, yonggang niu, xiaolong tang, dongqin li and qiang chen. "oxidative stress and antioxidant status in a lizard phrynocephalus vlangalii at different altitudes or acclimated to hypoxia." comparative biochemistry and physiology part a: molecular & integrative physiology 190,  (2015): 9-14.

58. yang, yongzhi, lizhong wang, jin han, xiaolong tang, ming ma, kun wang, xiao zhang, qian ren, qiang chen and qiang qiu. "comparative transcriptomic analysis revealed adaptation mechanism of phrynocephalus erythrurus, the highest altitude lizard living in the qinghai-tibet plateau." bmc evolutionary biology 15, no. 1 (2015): 101.

57. xin, ying, xiaolong tang, huihui wang, songsong lu, yan wang, yang zhang and qiang chen. "functional characterization and expression analysis of myoglobin in high-altitude lizard phrynocephalus erythrurus." comparative biochemistry and physiology part b: biochemistry and molecular biology 188,  (2015): 31-36.

56. wang, cui, xiaolong tang, ying xin, feng yue, xuefeng yan, bingbing liu, bei an, xi wang and qiang chen. "identification of sex chromosomes by means of comparative genomic hybridization in a lizard, eremias multiocellata." zoological science 32, no. 2 (2015): 151-156.

55. lu, songsong, ying xin, xiaolong tang, feng yue, huihui wang, yucheng bai, yonggang niu and qiang chen. "differences in hematological traits between high-and low-altitude lizards (genus phrynocephalus)." plos one 10, no. 5 (2015).




54. yuan fang, shuo li , huabin zhou, xiaozhu tian, shuangyu lv, qiang chen∗ opiorphin increases blood pressure of conscious rats through renin-angiotensin system (ras). peptides 55 (2014) 47-51

53. xin, ying, huihui wang, xiaolong tang, songsong lu, weixin li, yang zhang, shiwei liang and qiang chen. "characterisation and expression analysis of sox9 in the multiocellated racerunner, eremias multiocellata." asian herpetological research 2,  (2014): 004.




52. xiaolong tang, ying xin, huihui wang, weixin li, yang zhang, shiwei liang, jianzheng he, ningbo wang, ming ma and qiang chen*. "metabolic characteristics and response to high altitude in phrynocephalus erythrurus (lacertilia: agamidae), a lizard dwell at altitudes higher than any other living lizards in the world." plos one,  (2013).

51. xiaolong tang, f. yue, j. z. he, n. b. wang, m. ma, j. r. mo and q. chen. "ontogenetic and sexual differences of thermal biology and locomotor performance in a lacertid lizard, eremias multiocellata." zoology (jena) 116, no. 6 (2013): 331-5.

50. he, j., m. xiu, xiaolong tang, f. yue, n. wang, s. yang and q. chen. "the different mechanisms of hypoxic acclimatization and adaptation in lizard phrynocephalus vlangalii living on qinghai-tibet plateau." j exp zool a ecol genet physiol 319, no. 3 (2013): 117-23.

49. he, j., m. xiu, xiaolong tang, n. wang, y. xin, w. li and q. chen. "thermoregulatory and metabolic responses to hypoxia in the oviparous lizard, phrynocephalus przewalskii." comp biochem physiol a mol integr physiol 165, no. 2 (2013): 207-13.

48. yang, s., yang, a., shao, t., su, s., chen, q.* (2013) synergistic analgesic effects between neuronostatin and morphine at thesupraspinal level. peptides 44: 105– 110

47. lv, s., yang, y., chen, q.* (2013) regulation of feeding behavior, gastrointestinal function and fluid homeostasisby apelin. peptides 44: 87– 92

46. mo, j., yang, a., chen, z., shao, t., zhang, y., & chen, q. (2013). neuronostatin ameliorates sodium taurocholate-induced acute pancreatitis in rats. digestive diseases and sciences, 58(10), 2903-2907.




45. tang, x., yue, f., ma, m., wang, n., he, j., chen, q.* (2012) effects of thermal and hydric conditions on egg incubation and hatchling phenotypes in two phrynocephalus lizards. asian herpetological research 3(3): 184-191

44. tang, x., yue, f., zhang, d., yan, x., xin, y., wang, c., chen, q.* (2012) the effect of operational sex ratio on sex allocation and neonate phenotype in a viviparous lizard eremias multiocellata amphibia-reptilia 33: 485-493

43. su, s., yang, a., yang, s., wang, n., lu, s., wang, h., chen, q.* (2012) intracerebroventricular administration of neuronostatin delays gastric emptying and gastrointestinal transit in mice. peptides 35: 31–35

42. lv, s., qin, y., wang, h., xu, n., yang, y., chen, q.* (2012) centrally administered apelin-13 induces depression-like behavior in mice. brain res bull 88(6):574-80.

41. tang, x., yue, f., yan, x., zhang, d., xin, y., wang, c., chen, q.* (2012) effects of gestation temperature on offspring sex and maternal reproduction in aviviparous lizard (eremias multiocellata) living at high altitude. journal of thermal biology 37: 438–444

40. yang, s., yang, a., su, s., wang, h., wang, n., chen, q.* (2012) neuronostatin induces hyperalgesia in formalin test in mice. neuroscience letters 506: 126–130

39. lv, s., yang, y., qin, y., mo, j., wang, n., wang, y., chen, q.* (2012) central apelin-13 inhibits food intake via the crf receptor in mice. peptides 33: 132-138

38. yue, f., tang, x., zhang, d., yan, x., xin, y., chen, q.* (2012) body temperature and standard metabolic rate of female viviparous lizard eremias multiocellata during reproduction. canadian journal of zoology 90: 79–84

37. xin, y., tang, x., yue, f., zhang, d., yan, x., wang, c., chen, q.* (2012) isolation and sequence analysis of sox genes from lizard eremias multiocellata. russian journal of genetics 48(1): 88-94




36. yang, a., ji, y., su, s., yang, s., lu, s., mi, z., yang, q., chen, q.* (2011) intracerebroventricular administration of neuronostatin induces depression-like effect in forced swim test of mice. peptides 32: 1948–1952

35. yang, a., ge, w., lu, s., yang, s., su, s., mi, z., chen, q.* (2011) central administration of neuronostatin induces antinociception in mice. peptides 32: 1893–1901

34. yan, x., tang, x., yue, f., zhang, d., xin, y., wang, c., chen, q.* (2011) influence of ambient temperature on maternal thermoregulation and neonate phenotypes in a viviparous lizard, eremias multiocellata, during the gestation period. journal of thermal biology 36: 187–192

33. 吕双瑜 杨爱民 修明慧 杨艳杰 陈强*  (2011) 侧脑室注射脂肪酸合成酶抑制剂c75对小鼠学习记忆的影响,中华行为医学与脑科学杂志 20(1):51-52

32. lv, s., yang, y., qin, y., xiong, x., chen, q.* (2011) effect of centrally administered apelin-13 on gastric emptying and gastrointestinal transit in mice. peptides 32: 978–982

31. yang, q., lu, s., tian, x., yang, a., ge, w., chen, q.* (2011) the antidepressant-like effect of human opiorphin via opioid-dependent pathways in mice. neuroscience letters 489: 131-135




30. yang, y., lv, s., xiu, m., xu, n., chen, q.* (2010) intracerebroventricular administration of apelin-13 inhibits distal colonic transit in mice. peptides 31: 2241–2246

29. zhang, d., yue, f., tang, x., chen, z., li, r., chen, q.* (2010) effect of gestation temperature on sexual and morphological phenotypes of offsprings in a viviparous lizard, eremias multiocellata. journal of thermal biology 35: 129–133

28. tian, x., chen, j., xiong, w., he, t., chen, q.* (2009) effects and underlying mechanisms of human opiorphin on colonic motility and nociception in mice. peptides 30:1348-54

27. xu, n., wang, h., fan, l., chen, q.* (2009) supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice. peptides 30: 1153–1157

26. li, l., lu, y., xiong, w., liu, j., chen, q.* (2008) effect of centrally administered c75, a fatty acid synthase inhibitor, on gastric emptying and gastrointestinal transit in mice. european journal of pharmacology 595: 90–94

25. chen, j., long, y., han, h., wang, t., chen, q.,* wang, r.* (2008) water-solutable derivates of propolis mitigates scopolamine-induced learning and memory impairment in mice. pharmacology, biochemistry and behavior 90:441-446

24. zai, k., hu, l., chen, j., fu, c., chen, q.* (2008) chrysin induced hyperalgesia via gabaa receptor in mice. planta medica 74:1229-1234

23. 欧阳建梅 陇源 房克难 王锐 陈强*, (2007) 蜂胶乙醇提取物(eep)对豚鼠胸主动脉的舒张作用, 现代生物医学进展 (9):1286-1289

22. zhao, q., chen, q., feng, y., lin,x., wang, r.* (2005) [tic4] endomorphins, analogues of endomorphins, have significantly nhanced vasorelaxant effects in rat aorta rings. protein pept. lett 12(4), 323-326                                                   

21. xu, p., chen, q., li, h., yu, y., yan, x., wang, r.* (2005) the relaxant effect of dobutamine on porcine coronary arterial ring segments. pharmazie 60 375-377                  

20. feng, y., zhao, q., chen, q., wang, r.* (2005) vasorelaxant responses to endomorphin1[ ], analogues of endomorphins, in rat aorta rings.yand endomorphine2[ pharmazie 60:851-855                                                       

19. fu, c., kong, z., wang, k., yang, q., zhai, k., chen, q.,* wang, r.* (2005) effects and mechanisms of supraspinal administration of rat/mouse hemokinin-1, a mammalian tachykinin peptide, on nociception in mice. brain research 1056, 51-58                        

18. zhao, q., chen, q., yang, d., feng, y., long, y., wang, p., wang, r.* (2005) endomorphin 1[c] and endomorphin 2[c], endomorphins analogues containing a reduced (ch2nh) amide bond between tyr1 and pro2, display partial agonist potency but significant antinociception. life sci., 77, 1155-1165                                                  

17. xu, p., chang, m., chen, l., chen, q.,* yan, x.,* wang, r.* (2004) the relaxant effect of nociceptin on porcine coronary arterial ring segment. can. j. physiol. pharmacol 82, 993-999                                                       

16. lin, x., chen, q., xue, l., ma, x., wang, r.* (2004) endomorphins, endogenous opioid peptides induce apoptosis in human leukemia hl-60 cells. can. j. physiol. pharmacol 82, 1018-1025                                                       

15. chen, l., fang, q., chen, q.,* guo, j., wang, z., chen, y., wang, r. * (2004) study in vitro and in vivo of nociceptin/orphanin fq(1–13)nh2 analogues substituting n-me-gly for gly2 or gly3. peptides 25, 1349-1354                                                 

14. lin, x., cai, y., li, z., chen, q., wang, r.*(2003) structure determination, apoptosis induction, and telomerase inhibition of cfp-2, a novel lichenin from cladonia furcata. biochim. biophys. acta 1622: 99                                 

13. lin, x., yang, d., cai, w., zhao, q., gao, y., chen, q., wang, r.* (2003) endomorphins, endogenous opioid peptide, provide antioxidant defense in the brain against free radicall-induced damage. biochim. biophys. acta (bba)-mol. basis. dis 1639: 195                                      

12. chen, q., chen, y., chen, l., yang, d., dong, s., wang, r.* (2001) the effects of the synthetic nocistation on blood vessel activities. chin. sci. bull 46(8): 275                                      

11. 吴宁, 霍笑风, 陈强, 杨顶建, 王 锐* (2001) 侧脑室注射内吗啡肽-1对麻醉大鼠血压的影响. 药学学报 36(10): 731"                                                 

10. 吴宁, 任维华, 霍笑风, 陈强, 王 锐* (2001) 内吗啡肽及其类似物对心血管系统的作用. 药学学报 36(4): 241                                                     

9. 陈勇, 陈鲤翔, 陈强, 杨顶建, 彭雅丽, 杨祺, 王 锐* (2001) 痛稳素碳末端八肽翻转孤啡肽对抗吗啡镇痛的作用. 中国药理学通报17(4): 383                                                  

8. chen, q., chen, l., chen, y., yang, d., peng, y., dong, s., wang, r.* (2000) effects of the synthesized nocistatin and nocistatin (10-17) on analgesia induced by endomorphin-1 and endomorphin-2. acta pharmacol. sin 21(11): 1053"

7. 陈强, 陈勇, 陈鲤翔, 杨顶建, 董守良, 王 锐* (2000) 痛稳素的合成及其对血管活性的影响. 科学通报 45(24): 2620)                                                    

6. chen, q., chang, c., liu, n., e. randi, v. licchini, mitochondrial dna intro-gression between two parapatric species (alectoris) in central china动物学报1999,45(4):456      

5. 陈强, 李仁德, 刘迺发, (1999) 雄性密点麻蜥精巢支持细胞和间质细胞的年周期变化. 兰州大学学报 35(专辑)80-82                                                        

4. li, r., chen, qiang., liu, n. (1998) effects of body temperature on electrocardiograms of lizard eremias multiocellata. 动物学研究 19(4): 269-276                                                  

3. 李仁德, 陈强, 刘迺发, (1996) 温度对蜥蜴血红蛋白及血浆总蛋白浓度的影响, 动物学报, 42(3):247-252                                                   

2. 陈强, (1995) 丽斑麻蜥和草原沙蜥静止代谢率的研究, 兰州大学学报(自然科学版), 31(1):68-71                                                   

1. 陈强, 韩昭雪, (1993) 变色沙蜥繁殖的研究, 兰州大学学报(自然科学版) 29(4):199- 204


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